Humans have adapted to meet their water needs across disparate environments over time using behavioral adaptations. Yet, as temperatures rise and freshwater sources become depleted, it is critical to understand 1) how populations modify their environments to meet their water needs, and 2) the consequences of these anthropogenic - or human caused changes - on the environment and further on human health. This talk will provide an overview of different global water challenges and focus on a couple of case studies to highlight how development projects in remote areas that provide easier access to water, which may be high in salt or other contaminants, can unintentionally worsen health outcomes and hasten water depletion. (#37908)