Dr. Steven Seyedin presents an overview of PSA recurrence and risk factors for assessment. A PSA test is a blood test used to detect prostate-specific antigen (PSA) levels in the blood, which can be elevated in cases of prostate cancer and is a common screening tool. He explains how PET, CT, and MRI work, highlighting the precision of PSA PET in detecting cancer spread by targeting PSA proteins on tumor cells. This imaging method combines PET and CT to reveal metastatic disease with greater accuracy than traditional scans. Seyedin addresses the strengths of different imaging agents, emphasizing that access, not brand, is key. He also cautions against false positives, especially in bone lesions, which can mislead diagnosis. By improving staging accuracy, PSA PET supports better treatment planning and outcomes. Ongoing studies explore its use earlier in diagnosis, potentially replacing biopsy or MRI in select cases. Recorded on 05/02/2025. (#40805)