Experience is the engine that drives much of postnatal brain development. When children are deprived of key (i.e., experience-expected) experiences, particularly during critical periods of development, brain and behavioral development can be derailed. There is perhaps no more egregious form of deprivation than being raised in large, state-run institutions. Charles Nelson (Harvard Medical School) discusses the Bucharest Early Intervention Project, a long-term study that includes infants abandoned to institutions. Recorded on 10/11/2019. (#35285)