Working with Natural Born Killers: Using Natural Killer Cells to Improve Cancer Immunotherapies

11/19/2019; 13 minutes

Natural Killer - or NK - cells are one of our immune systems most potent defenses, able to attack viral infections and destroy cells that exhibit tumorigenic characteristics. UC San Diego physician Dr. Dan Kaufman, who has specialized in treating blood cancers for over 20 years now leads a research group at the UC San Diego Stem Cell program that is using induced pluripotent stem cells to generate NK cells that are targeted to destroy cancer cells. With the goal of providing safer, more effective, off-the-shelf cancer immunotherapies, the methods his lab has developed are being employed in a first-of-its-kind clinical trial anywhere in the world being conducted at the UC San Diego Moores Cancer Center.
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